Lead and execute cell-free DNA synthesis experiments from concept to validation.

Design and optimise experiments using Design of Experiments (DOE) methodologies to produce actionable results.

Contribute to the grant writing process, supporting technical sections and experimental justifications.

Collaborate closely with hardware engineers to integrate biological workflows into automated systems.

Proactively identify challenges, propose solutions, and drive scientific processes with minimal oversight.

Maintain detailed experimental documentation and contribute to project reporting for internal and external stakeholders.

Requirements

The ideal candidate will have:

Proven, hands-on wet lab expertise with standard and advanced experimental techniques and instrumentation.

Demonstrated use of results-driven DOE in experimental design.

Familiarity with the grant writing process for research funding.

Comfortable owning and driving scientific processes independently.

It would be nice if the candidate has:

Hands-on expertise across multiple DNA synthesis techniques, both enzymatic (e.g., Gibson Assembly, Rolling Circle Amplification) and chemical (e.g., phosphoramidite chemistry).

Experience with RNA synthesis workflows.

Exposure to integrating hardware and biology (automation, robotics, lab instrumentation).

Experience with fluorescence spectroscopy.

Experience with cell culture techniques and ELISA assays.

A proven track record of self-driven, end-to-end scientific projects.

About the Company

AmpliSynth is developing SynthBox, a modular, open-source DNAprinter that enables same-day DNA synthesis without the bottlenecks of traditional supply chains. Their mission is to democratise access to
custom DNA and accelerate breakthroughs in biotechnology.

Why Join Amplisynth?

- Contribute to meaningful projects that will make the world a better place
- Work in a collaborative, diverse, and international team
- Flexible working hours and great creative freedom.
- Opportunity to be at the forefront of next generation DNA synthesis technology.
- Competitive Salary and Benefits (Pension, Bonus, etc)

The job offers hybrid working with remote work. There is an option to work in the office based in London but Amplisynth offers a fully flexible working arrangement - where hours are dictated by the candidate, so that the candidate can work in their most comfortable hours without additional stress.

Interview process

This will be a 2-3 stage process. The first stage is an exploratory interview, then there will be one or two further interviews testing real case scenarios. None of the interviews requires preparation.

How to Apply

Please send your CV and a short note explaining your relevant experience to HR@Amplisynth.com , before the 15th September 2025. For question and inquiries about this position please contact Lisa Schmidt lisaschmidt@amplisynth.com

Posted 8th of August